jueves, 30 de junio de 2016

Stem Cell Therapy Treats Kidney Disease and Kidney Failure - Treating Chronic Kidney Disease with Food

Stem Cell Therapy Treats Kidney Disease and Kidney Failure




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Stem cell therapy for kidney failure
Kidney failure manifests itself when the kidneys
cannot filter water products from the blood.
This in turn may lead to swelling of the body,
increased levels of acid, potassium and phosphate,
and decreased levels of calcium. Kidney failure
is associated with bone and cardiovascular
diseases. The two main forms of kidney failure
are acute kidney injury, which is often reversible
with adequate treatment, and chronic kidney
disease, which is often not reversible.
Stem cell therapy for kidney diseases
Different types of cells from the bone marrow
have been tested in animals and in clinical
studies for potential use in kidney disease.
Out of all the cells investigated, mesenchymal
stem cells (MSCs) have shown the most promising
results till now. Studies suggest that MSCs
may be able to enhance the kidney’s ability
to repair itself.
MSCs from the bone marrow can produce specialized
bone, fat and cartilage cells. Researchers
investigating the therapeutic MSCs effects
within the kidney have suggested that these
cells
may release proteins that can stimulate kidney
cell growth, inhibit cell death and that could
encourage the kidney’s own stem cells to
repair the damage. Further research is needed
to
establish whether these ideas are correct
and how they could lead to a treatment for
patients.
Who is a good candidate for stem cell therapy
for kidney failure?
Although stem cell therapy promises to be
a solution for many people suffering from
various
kidney problems, that doesn’t mean that
anybody can benefit from it. There are a series
of
conditions that qualify a patient for being
eligible for stem cell therapy:
Firstly the doctor must assess the condition
of the patient based on his medical history
and
prior treatments. Secondly the patient must
be able to withstand traveling to the country
where the therapy
will be administered. The patient will also
need to be able to stay in the country where
the treatment is
administered for the duration of the treatment.
When using fat stem cells, the patient will
have to be able to support a minor liposuction
procedure.
Some of the benefits may include faster healing
time, reduction of the transplant rejection
rate, the elimination of the need for cadaveric
donors and many others. This kind of therapy
could be employed in detecting and healing
diseases from fetal stages and also can prevent
the
apparition of congenital diseases from an
early age. Stem cell therapy is truly a ground
breaking
success for medicine, if done right, but careful
testing is needed.

https://www.youtube.com/watch?v=IYzCQdhXXfo


Treating Chronic Kidney Disease with Food




andquot;Treating Chronic Kidney
Disease with Foodandquot;
In the United States approximately one
in three adults aged 65 years and older
has chronic kidney disease.
But the majority of patients with
chronic kidney disease do not
progress to the advanced stages
because death precedes the progression
to end-stage renal disease.
Following about a thousand folks
65 or older
with chronic kidney disease
for about a decade,
only a few had to go on dialysis, because
most had to go underground.
The scariest thing for many kidney
patients is the fear of dialysis,
but they may be 13 times more
likely to die than dialysis.
With deaths from heart disease
killing more than nearly all other
causes combined, decreasing
kidney function can just set one up
for heart attacks, strokes, and death.
That's why it's critical that any diet
chosen to help the kidneys
must also help the heart.
A plant-based diet fits the bill, providing
protection against kidney cancer,
and kidney stones, and kidney
inflammation, and acidosis,
as well as heart disease.
Namely, blood pressure
control may be favored
by the reduction of sodium intake
and the vegetarian nature of the diet,
which is very important also for
lowering serum cholesterol,
which may not only help the heart
but the kidneys themselves.
All the way back in 1858, Virchow,
the father of modern pathology,
was the first to describe the fatty
degeneration of the kidney.
In 1982 this idea of lipid
nephrotoxicity was formalized,
the possibility that fat and cholesterol
in the bloodstream could be toxic
to the kidneys directly, based on data
like this showing plugs of fat
literally kind of clogging up the
works in autopsied kidneys.
Since the notion was put forth
it has gained momentum.
It appears high cholesterol and
fat in the blood may accelerate
progression of chronic kidney disease
through direct toxic effects
on the kidney cells themselves.
Given the connection between
cholesterol and kidney decline,
the use of cholesterol-lowering
statin drugs has been recommended
to slow the progression
of kidney disease.
Of course, serious adverse effects on
muscle and liver must be kept in mind.
That's why plant-based diets could
offer the best of both worlds,
protecting the heart and the kidneys
without drug side effects.
The two potential drawbacks
are the amount of phosphorus
and potassium
in plant foods,
which ailing kidneys can sometimes
have a problem getting rid of.
But it turns out that the phosphorus
in meat is absorbed
at about twice the rate,
not to mention the phosphate additives
that are injected into meat.
So eating vegetarian can significantly
lower phosphorus levels in the blood.
The concern about potassium
is largely theoretical,
since the alkalizing effects of plant
foods help the body excrete potassium,
but not theoretical for those on
dialysis or with end-stage disease,
who need to be followed closely
by a dietitian kidney specialist.
Special protein-restricted vegan diets
have been used successfully
to slow or stop the progression
of kidney failure.
Here is the declining kidney function
of eight diabetics for one to two years
before switching to the plant based
diet, which appeared to stop
the inexorable decline in most of the
patients, leading the researchers
to proclaim it is the treatment of
choice for diabetic kidney failure.
It may help delay dialysis
by one to two years,
and after kidney transplant may
improve the survival of the kidney,
and improve the survival of the patient.
Most of the papers, though, are
just pilot feasibility studies.
Doesn't matter if it's effective if we
can't get people to stick to the diet.
But while we're waiting for
more definitive studies,
existing data support offering these
kinds of plant-based diets as an option
to all patients with advanced or
progressive chronic kidney disease.
Even if the effects of such diets on
the progression of kidney failure
are still debatable, the unquestionably
beneficial favorable effects
of plant-based diets on some of
the most deleterious cardiovascular
and metabolic disorders usually
associated with renal failure
like hypertension and diabetes provide
rationale for recommending
a predominance of plant proteins
for patients with failing kidneys.
Yet, diet is still underutilized,
in part because some people find
changing their diet is difficult.
Yet we know foods rich in animal
protein lead to metabolic acidosis.
Our diets are largely acid-producing
because they are deficient
in fruits and vegetables and contain
large amounts of animal products.
And so what did doctors do?
They gave people baking soda.
Instead of treating the cause,
the dietary acid load
from too many animal products
and too few fruits and vegetables,
they treated the consequence by saying,
andquot;Oh, too much acid? Well, we'll just give
you some base, sodium bicarbonate.andquot;
And it works.
Neutralization of dietary acid with
sodium bicarb decreases kidney failure
and slows kidney function decline,
but sodium bicarbonate
(baking soda) has sodium,
so doctors may be just
adding another problem.
Now if patients are not going
to cut back on animal products,
at least they should be eating
more fruits and vegetables.
And so they tried that,
and look, it worked too,
and with it doing so without leading
to too much potassium in the blood.
And may even work better,
as fruits and vegetables
have the additional advantage of
helping to lower blood pressure.
This study is important because it illustrates
a very simple and safe way
to treat metabolic acidosis:
fruits and vegetables.
So the key to halting the progression
of chronic kidney disease
might be in the produce market,
not in the pharmacy.

https://www.youtube.com/watch?v=MxAFV6XESkM

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