Renal Hemodynamics Animation - Kidney Disease – Obvious (Spanish, :15)

Renal Hemodynamics Animation




>> Male Speaker: In order to
understand the risk that NSAIDs
post to the kidneys, it is
critical to understand kidney
hemodynamics, the pressure
and flow of blood
through the kidney.
Each kidney is made up of
about one million filtering
units called nephrons.
The glomerulus is the
portion of the nephron where
filtering takes place.
Blood flows into each
glomerulus via an afferent
arteriole and out via and
efferent arteriole.
The tone of these arterioles
alters the pressure
within each glomerulus,
and regulates filtration.
In other words, the relative
vasoconstriction or vasodilation
of the afferent and efferent
arterioles determines the
pressure within each glomerulus,
and it is that pressure that
pushes fluids and small
molecules out of the capillary,
and into the tubular
lumen of the nephron.
The renin-angiotensin system is
activated by decreased blood
flow to the kidney, the
resultants rise in angiotensin
two constricts the efferent
arterioles and raises
the glomerular capillary
pressure and maintains
glomerular filtration rate.
Renin-angiotensin system
blockers such as ace
inhibitors and angiotensin
receptor blockers,
block this action and lower
glomerular capillary pressure.
This may be protective in
chronic kidney disease,
especially diabetes.
However, in states of volume
loss and decreased kidney
profusion, such as congestive
heart failure, trauma,
cirrhosis, acute
volume depletion,
or acute gastroenteritis,
the use of these drugs
may decrease glomerular
pressure and GFR.
In these same states
of volume depletion,
prostaglandins may
preserve kidney profusion
and GFR by dilating
the afferent arterioles.
However, NSAIDs block
this protective action
of prostaglandins and may
also decrease glomerular
pressure and GFR.
Together, the use of NSAIDs
and renin-angiotensin system
blockers may result in both
afferent vasoconstriction and
efferent vasodilation and lead
to a dramatic decrease
in glomerular pressure and GFR,
causing acute kidney injury.

https://www.youtube.com/watch?v=J2YaULhMx5g


Kidney Disease â€" Obvious (Spanish, :15)




los factores de riesgo de la enfermedad
renal los tiempos tan obvia ellos saben
los podría salvarle la vida en aquellos
lugares que su familiar con problemas de
deuda
es así que hace que una persona
informes de máxima los 15 puntos

https://www.youtube.com/watch?v=KmXwCTuWe7M